Publications and metrics


Total citations as of July 2025


Peer-reviewed Journal Papers

Bougioukas KI, Liakos A, Tsapas A, Ntzani E, Haidich A-B. Preferred reporting items for overviews of systematic reviews including harms checklist: a pilot tool to be used for balanced reporting of benefits and harms. Journal of Clinical Epidemiology 2018;93:9–24. doi: 10.1016/j.jclinepi.2017.10.002.

Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Experimental Gerontology 2018;108:166–73. doi: 10.1016/j.exger.2018.04.013.

Bougioukas KI, Bouras E, Apostolidou-Kiouti F, Kokkali S, Arvanitidou M, Haidich A-B. Reporting guidelines on how to write a complete and transparent abstract for overviews of systematic reviews of health care interventions. Journal of Clinical Epidemiology 2019;106:70–9. doi: 10.1016/j.jclinepi.2018.10.005.

Bouras E, Karakioulaki M, Bougioukas KI, Aivaliotis M, Tzimagiorgis G, Chourdakis M. Gene promoter methylation and cancer: An umbrella review. Gene 2019;710:333–40. doi: 10.1016/j.gene.2019.06.023.

Delli FS, Sotiriou E, Lazaridou E, Apalla Z, Lallas A, Vakirlis E, Gerou S, Bougioukas KI, Ioannides D. Total IgE, eosinophils, and interleukins 16, 17A, and 23 correlations in severe bullous pemphigoid and treatment implications. Dermatologic Therapy 2020;33:e13958. doi: 10.1111/dth.13958.

Bougioukas KI, Bouras EC, Avgerinos KI, Dardavessis T, Haidich A-B. How to keep up to date with medical information using web-based resources: a systematised review and narrative synthesis. Health Information & Libraries Journal 2020;37:254–92. doi: 10.1111/hir.12318.

Bougioukas KI, Vounzoulaki E, Mantsiou CD, Savvides ED, Karakosta C, Diakonidis T, Tsapas A, Haidich A-B. Methods for depicting overlap in overviews of systematic reviews: An introduction to static tabular and graphical displays. Journal of Clinical Epidemiology 2021;132:34–45. doi: 10.1016/j.jclinepi.2020.12.004.

Karakosta C, Bougioukas KI, Karra M, Kontopanos G, Methenitis G, Liaskou M, Paraskevopoulos K, Kokolaki A. Changes in astigmatism after horizontal muscle recession strabismus surgery: A retrospective cohort study. Indian Journal of Ophthalmology 2021;69:1888–93. doi: 10.4103/ijo.IJO_3228_20

Bougioukas KI, Vounzoulaki E, Mantsiou CD, Papanastasiou GD, Savvides ED, Ntzani EE, Haidich A-B. Global mapping of overviews of systematic reviews in healthcare published between 2000 and 2020: a bibliometric analysis. Journal of Clinical Epidemiology 2021;137:58–72. doi: 10.1016/j.jclinepi.2021.03.019

Gates M, Gates A, Pieper D, Fernandes RM, Tricco AC, Moher D, Brennan S E, Li T, Pollock M, Lunny C, Sepúlveda D, McKenzie JE, Scott SD, Robinson KA, Matthias K, Bougioukas KI, Fusar-Poli P., Whiting P, Moss SJ, & Hartling L. Reporting guideline for overviews of reviews of healthcare interventions: development of the PRIOR statement. BMJ, 378, 2022:e070849. doi: 10.1136/bmj-2022-070849

Karassa FB, Bougioukas KI, Pelechas E, Skalkou A, Argyriou E, Haidich A-B. Pharmacological treatment for connective tissue disease-associated interstitial lung involvement: Protocol for an overview of systematic reviews and meta-analyses. PLOS ONE 2022;17:e0272327. doi: 10.1371/journal.pone.0272327.

Georgoulis V, Haidich A-B, Bougioukas KI, Hatzimichael E. Efficacy and safety of carfilzomib for the treatment of multiple myeloma: an overview of systematic reviews. Critical Reviews in Oncology/Hematology 180, 2022:103842. doi: 10.1016/j.critrevonc.2022.103842

Karakosta C, Paraskevopoulos K, Bisoukis A, Bougioukas KΙ, Kokolaki A. Straatsma Syndrome: A Case Series. Cureus 2022;14(9): e29779. doi: 10.7759/cureus.29779.

Pagkalidou E, Doundoulakis I, Apostolidou-Kiouti F, Bougioukas KI, Papadopoulos K, Tsapas A, et al. An overview of systematic reviews on imaging tests for diagnosis of pulmonary embolism applying different network meta-analytic methods. Hellenic Journal of Cardiology 2023. doi: 10.1016/j.hjc.2023.05.006

Pamporis K, Karakasis P, Bougioukas KI, Simantiris S, Sagris M, Bougioukas KI, Tousoulis D. Effectiveness and safety of injectable PCSK9 inhibitors in dyslipidaemias’ treatment and cardiovascular disease prevention: an overview of 86 systematic reviews and a network meta-analysis. Clínica e Investigación en Arteriosclerosis 2023. doi: 10.1016/j.arteri.2023.11.003

Karakasis P, Patoulias D, Pamporis K, Stachteas P, Lefkou E, Bougioukas KI, et al. Risk of subclinical atherosclerosis in primary Sjogren’s syndrome: A systematic review and meta-analysis. European Journal of Internal Medicine 2023;0. doi: 10.1016/j.ejim.2023.11.007.

Karakasis P, Bougioukas KI, Pamporis K, Fragakis N, Anna-Bettina Haidich A-B. Appraisal methods and outcomes of AMSTAR 2 assessments in overviews of systematic reviews of interventions in the cardiovascular field: A methodological study. Research Synthesis Methods. 2023. doi: 10.1002/jrsm.1680

Mainou M, Bougioukas KI, Malandris K, Liakos A, Klonizakis P, Avgerinos I, et al. Reporting of adverse events of treatment interventions in multiple myeloma: an overview of systematic reviews. Ann Hematol 2023. doi: 10.1007/s00277-023-05517-7.

Heise V, Holman C, Lo H, Lyras EM, Adkins MC, Maria Raisa Jessica Aquino, Bougioukas KI, O. Bray K., et al. Ten simple rules for implementing open and reproducible research practices after attending a training course. Plos Computational Biology. 2023;19:e1010750 doi: 10.1371/journal.pcbi.1010750.

Bougioukas KI, Pamporis K, Vounzoulaki E, Karagiannis T, Haidich A-B. Types and associated methodologies of overviews of reviews in healthcare: a methodological study with published examples. Journal of Clinical Epidemiology 2023;153:13–25. doi: 10.1016/j.jclinepi.2022.11.003.

Bougioukas KI, Diakonidis T, Mavromanoli AC, Haidich A-B. ccaR: a package for assessing primary study overlap across systematic reviews in overviews. Research Synthesis Methods. 2023; 14(3):443–454. doi: 10.1002/jrsm.1610.

Chatzidimitriou K, Papaioannou W, Seremidi K, Bougioukas K, Haidich A-B. Prevalence and association of gastroesophageal reflux and dental erosion: An overview of reviews. Journal of Dentistry 133, 2023:104520. doi: 10.1016/j.jdent.2023.104520.

Karakasis P, Lefkou E, Pamporis K, Nevras V, Bougioukas KI, Haidich A-B, et al. Risk of subclinical atherosclerosis in patients with antiphospholipid syndrome and subjects with antiphospholipid antibody positivity: A systematic review and meta-analysis. Current Problems in Cardiology 2023; 48(6):101672. doi: 10.1016/j.cpcardiol.2023.101672.

Pamporis K, Bougioukas KI, Karakasis P, Papageorgiou D, Zarifis I., Haidich A-B. Overviews of reviews in the cardiovascular field underreported critical methodological and transparency characteristics: a methodological study based on the PRIOR statement. Journal of Clinical Epidemiology 2023;159:139–150. doi: 10.1016/j.jclinepi.2023.05.018.

Karakasis P., Pamporis K., Stachteas P. Patoulias D, Bougioukas KI, Nikolaos Fragakis N. Efficacy and safety of sodium-glucose cotransporter-2 inhibitors in heart failure with mildly reduced or preserved ejection fraction: an overview of 36 systematic reviews. Heart Fail Rev 2023;28(5):1033–1051. doi: 10.1007/s10741-023-10324-3.

Fouza A, Tagkouta A, Daoudaki M, Stangou M, Fylaktou A, Bougioukas K, et al. Exploring Perturbations in Peripheral B Cell Memory Subpopulations Early after Kidney Transplantation Using Unsupervised Machine Learning. Journal of Clinical Medicine 2023;12(19):6331. doi: 10.3390/jcm12196331.

Karakasis P, Patoulias D, Pamporis K, Stachteas P, Bougioukas KI, Klisic A, et al. Safety and efficacy of the new, oral, small-molecule, GLP-1 receptor agonists orforglipron and danuglipron for the treatment of type 2 diabetes and obesity: systematic review and meta-analysis of randomized controlled trials. Metabolism 2023;149:155710. doi: 10.1016/j.metabol.2023.155710.

Karakasis P, Patoulias D, Pamporis K, Popovic DS, Stachteas P, Bougioukas KI, et al. Efficacy and safety of once-weekly versus once-daily basal insulin analogues in the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes, Obesity and Metabolism 2023; 25(12): 3648–3661. doi: 10.1111/dom.15259.

Karakasis P, Stalikas N, Patoulias D, Pamporis K, Karagiannidis E, Sagris M, Stachteas P, Bougioukas KI et al. Prognostic value of stress hyperglycemia ratio in patients with acute myocardial infarction: a systematic review with Bayesian and frequentist meta-analysis. Trends in Cardiovascular Medicine 2024. doi: 10.1016/j.tcm.2023.11.006.

Talimtzi P, Ntolkeras A, Kostopoulos G, Bougioukas KI, Pagkalidou E, Ouranidis A, et al. The reporting completeness and transparency of systematic reviews of prognostic prediction models for COVID-19 was poor: a methodological overview of systematic reviews. Journal of Clinical Epidemiology 2024;167:111264. doi: 10.1016/j.jclinepi.2024.111264.

Bougioukas KI, Karakasis P, Pamporis K, Bouras E, Haidich A-B. amstar2Vis: an R package for presenting the critical appraisal of systematic reviews based on the items of AMSTAR 2. Research Synthesis Methods 2024. doi: 10.1002/jrsm.1705.

Puchner KP, Giannakou V, Veizis A, Bougioukas K, Hargreaves S, Benos A, Kondilis E. COVID-19 vaccination roll-out and uptake among refugees and migrants in Greece: a retrospective analysis of national vaccination routine data. Public Health 2024; 229:84–87. doi: 10.1016/j.puhe.2024.01.010.

Seliniotaki AK, Bougioukas KI, Lithoxopoulou M, Moutzouri S, Diamanti E, Ziakas N, Mataftsi A. Mydriasis for retinopathy of prematurity screening in Europe: A cross-sectional online survey. European Journal of Ophthalmology 2024; 0:0–0. doi: 10.1177/11206721241234952.

Safouris A, Palaiodimou L, Katsanos AH, Kargiotis O, Bougioukas KI, Psychogios K, Sidiropoulou T, Spiliopoulos S, Psychogios M-N, Magoufis G, Turc G, Tsivgoulis G. Overview of systematic reviews comparing endovascular to best medical treatment for large-vessel occlusion acute ischaemic stroke: an umbrella review. Therapeutic Advances in Neurological Disorders 2004. doi: 10.1177/17562864241246938.

Pamporis K, Karakasis P, Sagris M, Zarifis I, Bougioukas KI, Pagkalidou E, Milaras N, Samaras A, Theofilis P, Fragakis N, Tousoulis D, Xanthos T, Giannakoulas G. Mineralocorticoid receptor antagonists in heart failure with reduced ejection fraction: a systematic review and network meta-analysis of 32 randomized trials. Current Problems in Cardiology 2024; 0:0–0. doi: 10.1016/j.cpcardiol.2024.102615.

Lunny C, Kanji S, Thabet P, Haidich A-B, Bougioukas KI, Pieper D. Assessing the methodological quality and risk of bias of systematic reviews: primer for authors of overviews of systematic reviews. BMJ Medicine 2024; 3. doi: 10.1136/bmjmed-2023-000604.

Seliniotaki AK, Lithoxopoulou M, Virgiliou C, Gika H, Dokoumetzidis A, Bougioukas KI, et al. Efficacy and Safety of Mydriatic Microdrops for Retinopathy of Prematurity Screening: The MyMiROPS Randomized Clinical Trial. JAMA Ophthalmology 2024. 10.1001/jamaophthalmol.2024.5462.

Bartzoulianou RC, Coleman AL, Wilson MR, Harris A, Bougioukas KI, Pappas T, et al. Factors Associated with Corneal Hysteresis in an Elderly White Population: The Thessaloniki Eye Study. Journal of Glaucoma 2025; doi: 10.1097/IJG.0000000000002541.

Karakosta C, Samiotaki M, Bisoukis A, Bougioukas KI, Panayotou G, Papaconstantinou D, et al. Differential Signaling Pathways Identified in Aqueous Humor, Anterior Capsule, and Crystalline Lens of Age-Related, Diabetic, and Post-Vitrectomy Cataract. Proteomes 2025;13:7. 10.3390/proteomes13010007.

Anestiadou E, Stamiris S, Ioannidis O, Symeonidis S, Bitsianis S, Bougioukas K, Karagiannis T, Kotidis E, Pramateftakis M-G, Mantzoros I, et al. Comparison of Negative Pressure Wound Therapy Systems and Conventional Non-Pressure Dressings on Surgical Site Infection Rate After Stoma Reversal: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Clinical Medicine 2025; 14(5):1654. 10.3390/jcm14051654.

Ying X, Bougioukas KI, Pieper D, Mayo-Wilson E. Weighted corrected covered area (wCCA): A measure of informational overlap among reviews. Research Synthesis Methods 2025; 16(4):701-708. 10.1017/rsm.2025.19.

Karvouniaris M, Koulenti D, Bougioukas KI, Pagkalidou E, Paramythiotou E, Haidich A-B. Nebulized Antibiotics for Preventing and Treating Gram-Negative Respiratory Infections in Critically Ill Patients: An Overview of Reviews. Antibiotics 2025; 14(4):370. 10.3390/antibiotics14040370.

   

Books and Chapters

Bougioukas K. Practical Statistics in Medicine with R (in progress; Chapman & Hall/CRC Press | Taylor & Francis Group) 2024.

 

 

Bougioukas K, Haidich A-B. Medical Biostatistics: Basic Concepts. In: Papademetriou V, Andreadis EA, Geladari C, editors. Manag. Hypertens. Curr. Pract. Appl. Landmark Trials, Cham: Springer International Publishing; 2019, p. 19–53. doi: 10.1007/978-3-319-92946-0_2.




International Conference Proceedings

Bougioukas KI, Diakonidis T, Mavromanoli A, Haidich AB. ccaR: a package for assessing primary study overlap across SRs in overviews. ESMARConf2023, 27-31 March 2023. [YouTube]

Bougioukas K, Vounzoulaki E, Mantsiou M, Savvides E, Karakosta C, Diakonidis T, Tsapas A, Haidich AB. Methods for depicting overlap in overviews of systematic reviews: The ccaR package. AUEB-NKUA-Indiana-FSFH Conference in Biostatistics & Health Analytics, Aegina, 4-6 July 2022.

Bougioukas KI, Pagkalidou E, Avgerinou E, Tsapas A, Ntzani E, Smyrnakis E, Haidich AB. Overviews of Systematic Reviews with drugs, herbal medicine or dietary supplements. 9th Conference of the Eastern Mediterranean Region of the International Biometrics Society (EMR‐IBS), Thessaloniki, Greece, 8-12 May 2017.

 

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